الفهرس 
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Abstract
In our study we aimed to assess serum HSP70 level in epileptic and febrile seizures children. Our study included 30 epileptic children (group I), 30 children with febrile seizures (group II) and 25 healthy children which serve as control group (group III).
In our study we excluded children with electrolyte disturbance, well known metabolic disorder, abnormal computed topography suggestive of acute brain disease or trauma, well known central nervous system infection and those with history of exposure to irradiation.
All children included in the study were subjected to clinical history taking, complete examination, as well as investigations including serum HSP70, serum levels of calcium, potassium and sodium.
Our study showed:
• Children with FS were significantly younger in age than epileptic and healthy control children.
• As regarding family history there was a significant difference between febrile seizures group and both epilepsy and control groups.
• Statistically significant decrease of serum calcium level in epileptic children than febrile and healthy controls.
• As regarding serum sodium level there was significant decrease in epileptic children than both febrile seizures and healthy control children.
• A significant increase of HSP70 level between epilepsy group and both febrile seizures and control groups.
• A significant increase HSP70 level in febrile seizures group in relation to healthy control group.
• There was a significant negative correlation between serum sodium level and HSP70 level in epilepsy group.
• A significant strong positive correlation between type of therapy and HSP70 level in epilepsy group.
• Our study showed that HSP70 may be with benefit in diagnosis of epilepsy, as HSP70 level was sensitive at 60ng/l and specific at 83.33ng/l and accurate at 71.67ng/l in epilepsy group.