الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Obesity in children and adolescents has become an increasing clinical and public health concern. Its prevalence has increased significantly worldwide with an alarming rise of its comorbidities as: diabetes, dyslipidemia, hypertension …. etc.
Among those comorbidities is vitamin D deficiency which is due to its sequestration in the fat cells. Vitamin D once recognized as a skeletal vitamin only is now questionable as it was found to affect many systems within the body and that its deficiency is associated with many comorbidities as rickets in children, osteomalacia in adults, muscle weakness, hypertension, autoimmune diseases, increase tendency for infections, insulin resistance and many other health complications.
The present study was a cross-sectional study done in Diabetes Endocrine and Metabolism Pediatric Unit (DEMPU), Pediatric Department, Menofia University. It included 60 obese children (≥ 95thBMI percentile for age and sex) with a mean age 6 years ± 2.2 and 60 non obese age and sex matched children taken as control with a mean age 6± 2.5.
The aim of this study was to evaluate the status of 25(OH) D and serum TSH among obese Egyptian children.
All children included in the study were subjected to a detailed history, complete physical examination, anthropometric assessment, body mass index evaluation and laboratory testing of serum 25(OH) D, serum TSH, CBC, urine and stool analysis.
The study showed that obese children and had lower levels of 25 (OH) D when compared to the controls.
In the obese group 25 (OH) D had a significant negative correlation with WC and Hip circumference and no correlation was found with BMI, Systolic BP and Diastolic BP.
In our study, it was noted that the mean TSH concentration was significantly higher in obese group compared with control group.
In conclusion obese children exhibit a state of hypovitaminosis D. Obesity is associated with hypothyroidism, TV watching and unhealthy eating habits. Further studies should be done to identify the effect of weight reduction on thyroid profile in obese children.