الفهرس 
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Abstract
Congenital hypothyroidism is defined as thyroid hormone deficiency present at
birth which may be due to thyroid dysgenesis or other causes.
Congenital hypothyroidism is one of the most common preventable causes of
mental retardation with a worldwide incidence of 1:4000 live births and delay
in diagnosis lead to physical and mental retardation.
An early diagnosis and adequate treatment from the first weeks of life result in
normal linear growth and intelligence.
The Egyptian Ministry of Health and Population started to implement the screening
program for CH in year 2000, and by the end of year 2003 all governorates were
covered.
Presentation is usually asymptomatic so neonatal Screening program plays an
important role in diagnosis and must be the only way of presentation in the coming
years as the early initiation of therapy is the cornerstone for better IQ, growth and
sexual maturation.
Approximately 10% of infants with CH have associated congenital anomalies.
Cardiac anomalies are most common, but anomalies of the nervous system and eye
have been reported.
Our study was objected both to detect the prevalence of CH among children in
Beni suef governorate which was 1/863 and to determine its association with other
extra thyroid anomalies .patients were subjected to thorough clinical examination
and investigation by Echocardiography and abdominal Ultrasound and thyroid scanning. Results revealed that congenital heart diseases were the most common
followed by Down syndrome then renal and musculoskeletal anomalies
No statistical significant difference existed between hypothyroid patients with
cardiac anomalies and those without regarding their height, weight and BMI.
Screening for associated congenital heart diseases by Echocardiography is of great importance to discover anomalies as early as possible and to prevent or delay complications.