الفهرس 
Intracytoplasmic Sperm InjectionOnly 14 pages are availabe for public view
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Abstract
Abstract
Introduction: Infertility is defined as the inability to become pregnant after 12 months of regular, unprotected intercourse. About 85% of couples conceive spontaneously within 12 months if having intercourse regularly. Generally, infertility evaluation should be offered to couples who have not conceived after one year of unprotected vaginal intercourse. Women older than 35 years or couples with known risk factors for infertility may warrant evaluation at six months.
Aim of the Work: The aim of this work is to assess the effect of air bubbles localization inside the uterus on embryo transfer outcome in ICSI cycles.
Methodology: Design: Prospective (cohort) study.
Setting: This study was conducted in assisted reproductive technology unit of Ain Shams University Hospital after approval of the research ethical committee from April 2015 to October 2016.
Population: Eighty two women undergoing ICSI were enrolled in and a written informed consent was obtained from each participant.
Results: This study included 82 cases undergoing ICSI, the distance between fundal endometrial surface and air bubbles was measured in all cases immediately after withdrawal of ET catheter and they were classified into two groups. group A included 41 cases with distance < 10 mm, group B included
41 cases with distance ≥ 10 mm.
Conclusion: This study demonstrated that the final position of air bubble used as an identifier of the position of the embryo at ET can be determinative for pregnancy rates. Clinical PRs were higher in cases with air bubbles < 10 mm from fundal endometrial surface. This study reported that characteristics of blastocysts morphology such as expansion, ICM and trophectoderm grading were higher in pregnant than non pregnant cases. So they can be used as predictors of pregnancy outcome in ICSI cycles.
Recommendations: Further studies with larger number of groups would be useful to evaluate whether additional blastocyst parameters such as inner cell mass size, shape and fragmentation, or measures of cell number, blastocyst diameter and blastulation timing could contribute to provide a more precise prediction of pregnancy rate. The final position of air bubble after ET can be used as a predictive of outcome in ICSI cycles.
Keywords: Air Bubbles Depth, Pregnancy Rate, ICSI Cycles