الفهرس | Only 14 pages are availabe for public view |
Abstract Introduction During critical illness, changes in circulating hormonal levels are a common phenomenon. These alterations are correlated with the severity and outcome of patients in intensive care unit (ICU). Thyroid hormone plays a key role in the maintenance of the body growth modulating metabolism and the immune system. Subsequent studies confirmed the association between NTIS and adverse outcome in patients with sepsis, multiple trauma, acute respiratory distress syndrome, respiratory failure and mechanically ventilated patients, as well as in unselected ICU patients. Aim of the Work: The aim of the study was to highlight the relation between thyroid dysfunction and morbidity and mortality in critically ill patients. Conclusion: Patients admitted to the intensive care unit (ICU) typically present with altered levels of circulating hormones. And one of these changes is the level of thyroid hormones which may affect 60 to 70% of critically ill patients these changes may affect patients with no previous intrinsic thyroid disease. Hormone replacement therapy in these patients seems not to be harmful, but there is no proven evidence that treating these patients is beneficial |