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العنوان
The Diagnostic And Prognostic Value Of Mitral Annular
Plane Systolic Excursion (MAPSE) As An
Echocardiographic Indicator Of Myocardial dysfunction
In Sepsis And Septic Shock /
المؤلف
Gomaa, Mohamed Saleh Sayed.
هيئة الاعداد
باحث / محمد صالح سيد جمعة
مشرف / ماهر أبو بكر الأمير
مناقش / محمد عبد الهادى
مناقش / علاء احمد عبد الحميد
الموضوع
The Dirtmeister.
تاريخ النشر
2017.
عدد الصفحات
122 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
جراحة
تاريخ الإجازة
6/4/2017
مكان الإجازة
جامعة الفيوم - كلية الطب - الجراحة العامة
الفهرس
Only 14 pages are availabe for public view

from 122

from 122

Abstract

Septic shock is the most severe form of sepsis and is one of the
most significant causes of death among critically ill patients.
Sepsis-induced myocardial dysfunction SIMD is one of the major
predictors of morbidity and mortality in sepsis; characterized with
left ventricular dilation, depressed ejection fraction, and recovery
within 10–7 days.
Mitral annular plane systolic excursion MAPSE has been
proposed as useful echocardiographic parameter for the
assessment of LV longitudinal function and correlates with global
systolic function of the LV; being the earliest marker of myocardial
injury and dysfunction and easily obtained even for the untrained
observer and in patients with poor acoustic windows.
MAPSE value is thought to be an independent tool for LV
systolic function assessment generally, as well as myocardial
injury in patients with sepsis induced myocardial dysfunction, and
also a predictor of mortality in patients with severe sepsis and
septic shock.
To test this, MAPSE, LVEF, and SOFA score were measured in
50 septic shock patients (of whom 28 were survivors and 22 were
non-survivors).
It was found that there was statistically significant negative
correlation between SOFA scores levels (mortality predictor) with
MAPSE values among group I survived patients (average; r – 0.95
with p-value <0.001), and the same results were shown among
group II non-survivor patients (average; r – 0.85 & 0.84 with pvalue
<0.001), with high percentage of non-survivor group had
MAPSE ˂ 9 mm, on the other hand high percentage of survivor
group had MAPSE ≥ 9 mm. and regarding ROC curves