الفهرس 
The Genus EnterococcusOnly 14 pages are availabe for public view
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Abstract
Enterococci have become resistant to a wide range of antibiotics which include glycopeptides like vancomycin. The rapid increase of vancomycin resistance compromises physicians’ ability to treat infections caused by these strains because the therapeutic options for VRE infections are very limited. Our aim in this study was to evaluate the efficacy of chromogenic VRE medium in detection and identification of vancomycin resistant enterococci.
The present study was conducted in Al Abasia Fever Hospital, El Sayed Galal Hospital, Tanta University Hospital and Kafr El Sheikh General Hospital. Sixty enterococcal isolates were collected (thirty vancomycin susceptible, eight ancomycin intermediate resistant and twenty two vancomycin resistant isolates). Identification of these isolates to genus level was confirmed. Antibiotic susceptibility pattern for enterococcal isolates was done using disc diffusion method, chromogenic medium and The MIC of vancomycin for vancomycin resistant and intermediate resistant isolates was determined by E test.
Identification of vancomycin resistant and intermediate resistant isolates to species level was done by HiStrep rapid identification kit and the VITEK-2 COMPACT system to confirm species identification of these isolates obtained by chromogenic media.
The most common isolated vancomycin resistant and intermediate resistant species was E. faecium (53.1%) followed by E. faecalis (40.6%). The highest rate of isolation of VRE was from urine (50.0%). VRE isolates were mostly recovered from ICUs (45.5), 41.7%, of the collected isolates were vancomycin resistant by disc diffusion method. Regarding E-test, out of fourty two vancomycin resistant and intermediate resistant by disc diffusion method 52.4% were resistant and 19% were intermediate resistant. HiChrome VRE had 100% sensitivity and 83.3% specificity in identifying vancomycin resistant enterococcal isolates, it have 100% sensitivity and specificity in identifying VRE. faecalis and VRE. faecium.
Conclusion: We can depend on chromogenic media in both detection and identification of vancomycin resistant enterococci.
Key words: Enterococci, Multidrug resistant enterococci, VRE, chromogenic media, Infection control of VRE.