الفهرس 
AcknowledgementOnly 14 pages are availabe for public view
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Abstract
Diabetes and obesity are major health problems worldwide. There is strong link
between them, and during the past two decades several positive correlations betweenthem have been recognized by many workers (Sentinelli et al., 2002; Lau and Muniandy, 2011; Shehzad et al., 2012). Obesity is a serious risk factor for insulin resistance leading to diabetes and other disorders. Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both (Haslam and James, 2005).
Curcumin, from the rhizomes of Curcuma longa, is characterized by its antidiabetic properties, among other healing properties primarily because it is a relatively safe and inexpensive. Curcumin and its derivatives affect most of aspects of diabetes;
including plasma insulin levels, hyperglycemia, hyperlipidemia, and pancreatic islet regeneration with enhanced insulin synthesis and secretion. The application of
curcumin for the treatment of experimental diabetes and its complications has passed
by several experiments but it was struggled by the poor bioavailability of natural curcumin (Rezq, 2014) that has been overcome in our research using liposomes.A liposome is an artificially prepared vesicle composed of a lipid bilayer. The liposome can be used as a vehicle for administration of nutrients and pharmaceutical drugs. Liposomes are composed of natural phospholipids, and may also contain mixed lipid chains with surfactant properties (Ray, 2012).