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العنوان
Synthesis of containing thiophene nucleus as potential antitumor agents /
المؤلف
El-Saed, Somaya Ali Mohammed.
هيئة الاعداد
باحث / سمية على محمد السعيد
مشرف / سعدية محمود العشرى
مشرف / إيمان راضى البندارى
مشرف / نادية صبري الجوھرى
مناقش / صافيناز السيد عباس
مناقش / عزة رشاد معروف
الموضوع
Antineoplastic antibiotics. Antineoplastic agents. Thiophene.
تاريخ النشر
2017.
عدد الصفحات
120 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأدوية (الطبية)
تاريخ الإجازة
01/04/2017
مكان الإجازة
جامعة المنصورة - كلية الصيدلة - Department of Pharmaceutical Chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

The thesis is divided into 5 parts:- Part I: (The introductory part) contains different classes of anticancer agents according to their mechanisms of action in addition to the different anticancer thiophene derivatives. Part II: includes the research objectives and the major aims that direct the theoretical and practical work. Part III: contains : The theoretical discussion of the experimental work. It discusses the different conditions for the preparation of the desired compounds. In vitro assay for anticancer evaluation. Part VI: represents the experimental part that discusses different methods that were used in this thesis for preparation of either the intermediated and final products. Moreover, the microanalytical and spectral data that confirm the structures of the newly synthesized compounds were summarized in this part. Part V : includes the list of 212 references and periodical literatures used in this thesis, covering the period of 1966-2015.