الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Sodium butyrate is a sodium salt of a volatile short chain fatty acid (butyric acid). Two experiments were carried out to investigate the effect of sodium butyrate in alleviating the deleterious effects of either the salmonella enteritidis experimental infection in broiler chicks and feeding of low protein diet as a way of poultry ration adulteration through evaluation of sodium butyrate effect on hematological, biochemical, antioxidant parameters, inflammatory marker as well as immunological and histopathological studies. The infected group showed normocytic normochromic anemia with significant increase in serum biochemical parameters related to liver injury (AST, LDH) and significant increase in the activity of ALP as an indicator of intestinal damage. Also the level of serum amyloid A was elevated as a biomarker of inflammation. Furthermore, MDA as oxidative damage biomarker showed significant increase. while CAT and Gpx were significantly decreased. Moreover, salmonella challenge and the low protein diet have immunosuppressive effects. Consequently, sodium butyrate alleviated the deleterious effect of both the challenge and the low protein diet by potent antioxidative, anti-inflammatory and immune stimulant effects.