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Abstract Corneal Collagen cross-linking with Riboflavin and UV-A irradiation stops progression of KC in all eyes with statistically significant reduction in the apex K value. It is a minimal invasive technique that modifies corneal stromal structures and increases corneal stability and postpones the need of lamellar keratoplasty or PK. - The use of CXL shows a significant improvement in UCVA and BCVA from the preoperative values. - The cylinder values at 6months examination are significantly reduced than the values preoperatively. - Pachymetry decrease1 months postoperative and showed gradually increase at the end of 6 months but still there is a significantreduction in pachymetry than preoperative values.- Stromal haze is the main complication which resolved within 4- 6 weeks.- Good and careful selection of the patients will give good results which includes: 1. Mild to moderate KC with maximum K reading less than 54 D. 2. Minimal corneal thickness more than 400 micron, however the hypoosmolar riboflavin solution can be used in thinner corneas with minimum stromal thickness of 323 μm. |