الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 76 |  |  |
| | | from | 76 | | |
Abstract
Diabetes Mellitus is a major risk factor for coronary artery disease, making patients prone to diffuse, multiple and rapidly progressive CAD and is significantly associated with higher rates of ischemic complications and recurrent revascularization in these patients.
The aim of this work was to compare the major adverse cardiovascular and cerberovascular events in diabetic patients with multivessel CAD undergoing revascularization either complete or incomplete by PCI with at least one DES versus CABG over 1 year.
This study was conducted on 264 patients of them 135 patients underwent CABG (85 patients with complete revascularization and 50 patients with incomplete revascularization) and 129 patients underwent PCI (60 patients with complete revascularization and 69 patients with incomplete revascularization).
All subjects were evaluated by history taking, clinical examination, and 12-lead ECG. Conventional echo was performed on all patients to assess left ventricular function. Coronary angiography data, PCI data and CABG data were recorded. MACCE either the primary outcome included combined major adverse cardiovascular and cerberovascular events (death from any cause, nonfatal MI and nonfatal stroke, TVR ) and the secondary outcomes included (nonfatal or fatal MI, nonfatal or fatal stroke, cardiovascular mortality, heart failure, need for revascularization or freedom of angina) were collected after 1 year follow up.
The results of this study showed:
1) The Primary outcome: there was no statistically significant difference between the PCI and CABG groups either complete or incomplete as in CABG group 11.1% of the patients had combined MACCE of whom 8.2% in the complete group and 16% in the incomplete group, but in PCI group 14% had combined MACCE of whom 8.3% in the complete group and 18.8% in the incomplete group.
2) The secondary outcome: there was no significant difference between the PCI and CABG groups either complete or incomplete regarding fatal MI, nonfatal MI, fatal stroke, nonfatal stroke, cardiovascular mortality, heart failure and target vessel revascularization but there was statistically significant difference between the PCI (complete and incomplete combined together )and CABG (complete and incomplete combined together) (p value=0.018*) but no statistical difference if compared separately as in CABG group 82.2% of the patients had no anginal pain of whom 78% in the complete group and 84.7% in the incomplete group but in PCI group 69.8% had no anginal pain of whom 63.8% in the complete group and 76.7% in the incomplete group.