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Abstract Technological advances have improved the accuracy of Removable Partial Denture to reduce plaque accumulation, unfavorable forces which affect the health of the abutment teeth, and bacterial accumulation. The development of new techniques such as Computer-aided design with selective laser sintering may contribute to improve oral health condition for individuals using removable partial denture. The aim of this study was to evaluate the effect of removable partial denture fabricated by CAD/SLS technique on oral environment at both clinical and cytological levels. For the clinical part of this study, six patients having maxillary bilateral partially edentulous areas with class III Kennedy classification modification 1 and having at least missing second premolar and first molar at both sides and indicated for RPD replacement with palatal strap major connector were selected. The patients were selected having healthy abutment teeth, good oral hygiene, acceptable maxillo-mandibular relationship, sufficient edentulous space, healthy peridontium of the retained teeth and favorable occlusion. But patients with systemic disorders, oral disease, occlusal discrepancy, bad oral habits, old age and smokers were excluded from the study. Every patient received a CO-CR removable partial denture designed and manufactured by CAD/SLS technique. Every patient has been exposed to periodontal therapy (scaling and root planning) and has been instructed for good oral hygiene. The fabrication of the metal framework included several stages comprising: designing of the frame work, scanning of master cast, selection of restoration type, automatic surveying, block out of the undercut, selection of the design of the meshwork, and that of the major connector, designing of the minor connector and occlusal rest, designing the clasp, technical procedure inside the EOS machine, finishing and polishing of the frame work. After finishing the frame work and intra oral try in, jaw relation, teeth selection and arrangement were done followed by insertion of the Removable Partial Denture. The resulting removable partial dentures were evaluated clinically and cytologically to check the interaction between oral environment and the removable partial denture at insertion time, 3 months and 6 months after denture insertion. The clinical evaluations included recording the scores of gingival index, plaque index, periodontal probing depth and clinical attachment level of each abutment. Data were collected, statistically analyzed and compared to each other. Also cytological evaluation has been performed through the light microscopeic examination of cytological smears of the oral epithelium covering the residual alveolar ridge at the three observation period. The following results were obtained 1- The accurate fit of well designed removable partial denture reduced the accumulation of plaque which did not exceed score 1 on plaque index scale during the full periods of follow up. 2- No signs of gingival inflammation or bleeding were observed allover the periods of the study. 3- For Clinical periodontal attachment level there was no significant changes during the study periods which could be related to the effectiveness of the design and the good fit of the denture which helped in reducing the plaque accumulation. |