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العنوان
Epidemiological Study of Toxoplasmosis and Cytomegalovirous among Children with Idiopathic Sensorineural Hearing Loss
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المؤلف
Said ,Nayera Salah El-Din .
هيئة الاعداد
باحث / نيرة صلاح الدين سيد الجنيدى
مشرف / ناديـــة محمــد كمــــال
مشرف / رشــا حمـدى الكباريتى
مشرف / شـــيرين أحمـــد المصــري
تاريخ النشر
2016.
عدد الصفحات
159.p;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الحنجرة
تاريخ الإجازة
1/10/2016
مكان الإجازة
جامعة عين شمس - كلية الطب - Audiology
الفهرس
Only 14 pages are availabe for public view

from 159

from 159

Abstract

Background: The accurate identification of the causes of sensorineural hearing impairment in children is very challenging. The recognition of the causes of sensorineural hearing impairment helps in better treatment and in possibility of prevention. The causes of hearing impairment have changed with infections being the least frequent in developed nations, whereas in developing nations they continue being a frequent risk factor. The most frequent infectious agents associated with hearing loss are Cytomegalovirus (CMV). Aims: To study the frequency of Toxoplasma gondii and Cytomegalovirus (CMV) in children with sensorineural hearing impairment. To evaluate the possible role of these infectious agents on the occurrence of Idiopathic sensorineural hearing impairment. Materials & Method: The study is an attempt to study relation between CMV and toxoplasmosis in occurrence of sensorineural hearing loss. This study was conducted on 82 children, 40 males and 42 females. Their age ranged from 1 to 15 years. Fifty two of these children (study group) had sensorineural hearing loss with unknown etiology (no risk factors), 20 children (control subgroup I) had sensorineural hearing loss but with a risk factor (possible etiology) and 10 children (control subgroup II) had conductive hearing loss. Results: ELISA is used to detect IgG and IgM antibodies for CMV and toxoplasmasois. Conclusion: Cytomegalovirus is a common viral infection. Majority of cases in study and control groups had past exposure to cytomegalovirus. Recommendations: Polymerase chain reaction (PCR) is needed to detect cytomegalovirus load in cases with hearing loss. More researches are needed to emphasis on infectious agent as a cause of hearing loss in children.