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العنوان
Comparative Study Between DOG-1 and C-KIT Expression in Gastrointestinal Stromal Tumors (GIST) /
المؤلف
Naga, Nehal Kamal Hashem.
هيئة الاعداد
باحث / نهال كمال هاشم نجا
مشرف / محمد مسعد الليتي
مناقش / امنية محمد كامل رزق
مناقش / ايمن محمد السقا
الموضوع
Pathology.
تاريخ النشر
2016.
عدد الصفحات
p 205. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأعصاب السريري
تاريخ الإجازة
21/9/2016
مكان الإجازة
جامعة طنطا - كلية الطب - Pathology
الفهرس
Only 14 pages are availabe for public view

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Abstract

The diagnosis of GISTs shows controversy regarding that although the diagnosis of GIST may be made by light microscopy, pathologists commonly employ a panel of IHC markers, including anti-CD34, smooth-muscle actin, desmin, S100 and c-kit, to confirm the diagnosis. However, making the diagnosis can be difficult for the c-kit negative cases and c-kit positive cases that exhibit the same morphological pattern of other mesenchymal tumors and also stain c-kit positive. The aim of this work was to compare between the immunehistochemical expression of DOG1 and C-KIT and their diagnostic efficacy in GISTs using the percentage ratio score and intensity score.