الفهرس 
AbortionOnly 14 pages are availabe for public view
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Abstract
CD4+CD25+regulatory T cells are known to play an important role in the development and maintenance of tolerance in peripheral tissues. They suppress antigen-specific immune responses and are important for allograft tolerance. During pregnancy the mother tolerates an allograft expressing paternal antigens (the fetus) requiring substantial changes in immune regulation over a programmed period of time. The percentage of CD4+CD25+ Treg cells has been observed to decrease to the levels of those in non-pregnant patients in the case of miscarriage. Estrogens have powerful effects on immune cells and regulate their proliferation, distribution and function. The aim of this work is to evaluate the E2 levels and CD4+ CD25+ Treg cells in cases of missed abortion to explore the correlation between these markers which might be a possible etiology for missed abortion.