الفهرس 
Hematopoietic stem cell transplantationOnly 14 pages are availabe for public view
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Abstract
HSCT has become the standard of care for many patients with defined congenital or acquired disorders of the hematopoietic system or with chemo- radio- or, immuno- sensitive malignancies (Appelbaum, 2007).
The HSCT-CI is being used to counsel patients about prognosis and to risk-stratify patients in studies examining outcomes after HSCT (Sorror and Estey, 2014).
FHCRC investigators have recently found high serum ferritin, low serum albumin, and low platelet count before HSCT to have independent prognostic impact on HSCT outcome that were additional to those of the HSCT-CI (Vaughn, , 2015).
The aim of this study is to show the relation between pre transplant parameters (serum ferritin, albumin, platelet count and CRP) and early complications of hematopoietic stem cell transplantation.
This study had been conducted on 30 patients(19 men and 11 women).The patients had age range from 18 to 60 years old(median 43 years), 26 patients underwent autologous hematopoietic transplants to treat high-risk or relapsing NHL, MM, relapsing HL, 4 patients underwent allogeneic HSCT to treat 1st CR AML, 2nd CR AML, MM.
We conclude that :
• The pre-transplant low platelet count was the only factor that affects NRM by statistically significant difference.
(P value: 0.046).
• Pre- transplant low platelet count affects mean survival time with statistically significant difference (P value : 0.024).
• There is high risk in patients with pre-transplant high CRP level to develop shock with statistically significant difference (P value:0.026).
• The high S. Ferritin and low S. Albumin and high CRP have no impact on NRM or OS.