الفهرس 
InfertilityOnly 14 pages are availabe for public view
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Abstract
O
varian failure is a natural consequence of the aging process. Approximately 10% of women deviate from age specific standards and before reaching menopause, suffer from premature ovarian aging (POA), also called occult primary ovarian insufficiency (Barad et al., 2007) POA represents a milder precursor stage to premature ovarian failure (POF).
Diminished ovarian reserve (DOR) is defined by elevated age specific baseline follicular stimulating hormone (FSH) levels and/or decreased antimullerian hormone (AMH) levels <1 ng/ml, indicative of DOR at all ages (Singer et al., 2009). The levels of FSH may vary in different women but the fertility potential decreases significantly when levels are >15 mIU/ml (Kara et al., 2013). Those women with FSH ≥15 but <40 mIU/ml with age under 40 years come under the definition of POA. Either in vitro fertilization (IVF) with donor oocytes or adoption is often advised as a last resort to treatment for such women with DOR (Barad et al., 2006).
Therefore, the aim of this study was to evaluate the effect of DHEA supplementation on ovarian reserve markers and clinical pregnancy rate in women with poor ovarian reserve who were undergone ICSI/IVF.
Pregnancy rate in ICSI are closely correlated to the number of retrieved oocytes, and less than an optimal number is associated with poor outcome. In our study we noted positive significant correlation between DHEA supplementation and (ovulation rate, numbers of retrieved oocytes, numbers of MII phase oocytes, numbers of fertilized embryos, and rate of good quality embryos), as all of them were increased significantly after 12 weeks of DHEA supplementation.