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العنوان
Autonomic Cardiac Changes in
Temporal Lobe Epilepsy/
المؤلف
Shehata,Raymond Saleh
هيئة الاعداد
باحث / ريمون صالح شحاتة
مشرف / سامية عاشور محمد
مشرف / احمد عبد المنعم جابر
مشرف / لبنى محمد النبيل
مشرف / وليد عبد العظيم الحمادى
مشرف / مها على محمد ندا
تاريخ النشر
2016.
عدد الصفحات
164.p;
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب النفسي والصحة العقلية
تاريخ الإجازة
1/10/2016
مكان الإجازة
جامعة عين شمس - كلية الطب - Neurology
الفهرس
Only 14 pages are availabe for public view

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from 166

Abstract

Background: epileptic patients suffer from many autonomic symptoms either during the seizure or in between seizures. Interictal autonomic cardiac changes may cause arrhythmia which may be life threatening.
Aim of the work: to recognize the presence of cardiac autonomic changes in patients with temporal lobe epilepsy and to find the relation between autonomic cardiac changes and different variables.
Patients and methods: twenty patients with well controlled TLE and twenty patients with uncontrolled TLE were subjected to standard 12-lead ECG and 24 hour holter ECG.
Results: QTc was significantly shorter in patients with uncontrolled TLE than in patients with well controlled TLE. Patients with uncontrolled TLE had a faster heart rate than patients with well controlled TLE. Patients with uncontrolled TLE showed significant less SDNN, rMSSD and PNN50 than those with well controlled seizures.On the other hand, LF and LF/HF ratio was significantly more in uncontrolled group than the controlled group.
Conclusion: there is an interictal alteration in autonomic control of the heart in TLE. This alteration is corrected with proper control of seizures
Abbreviations:- TLE temporal lobe epilepsy, ECG electrocardiogram, SDNN Standard deviation of all normal RR intervals in the entire 24 hr ECG recording,PNN50Percent of difference between adjacent normal RR intervals that are greater than 50 msec,rMSSDRoot mean square successive difference,LF low-frequency , HF high frequency.SUDEP sudden unexpected death in epilepsy.