الفهرس 
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Abstract
Jaundice is the most common and one of the most annoying
problems that can occur in newborn.
Hyperbilirubinemia may lead to severe morbidity as kernicterus.
The aim of work is to study the levels of adrenomedullin (AM) in
cases of neonatal hyperbilirubinemia.Seventy neonate were recruited
from urban and rural areas of Menoufiya and Qualiobyia
governorate.Each neonate and his mother were subjected to:
1-Demographic and socioeconomic data.
2-Pregnancy data:previous and current pregnancies and abortions.
3-Delivery history:previous and current deliveries type of
delivery,medication and complications.
4-Neonatal feeding:for current children.
5-Anthropometric measurement to neonate including weight,length ,
chest circumference and head circumference.
7-Thorough clinical examination.
8-Laboratory investigation including:
a) Complete blood count
b) CRP
c) Liver function(ALT,AST,serum albumin)
d) Total, direct and indirect bilirubin
e) Kidney functions(blood urea,serum creatinine)
f) Serum adrenomedullin
The study had revealed the following results:
*Male gender, infants exposed to anesthesia during delivery infants
delivered by ceasarean section,decreased weight of newborn,breast milk
feeding,increased hemoglobin and RBCs were associated with increased
risk of neonatal jaundice ,while maternal age ,number of WBCs and
platelets were not associated with increased risk of neonatal jaundice.
*Significant positive correlation was detected between serum total
bilirubin ,indirect bilirubin and direct bilirubin and AM levels.
*Adrenomedullin probably plays a significant role in preventing adverse
effects and neuronal injury steps of significant hyperbilirubinemia.
* Results of this study may be used in establishing reference values for
AM as there are very limited number of studies in newborns.