الفهرس 
Neonatal SepsisOnly 14 pages are availabe for public view
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Abstract
Neonatal sepsis remains a serious life-threatening disease the early and reliable diagnosis of sepsis in the neonate remains an important goal, but still no single marker of infection, apart from isolation of the microorganism, has been identified. Between the most important features of sepsis, contributing significantly to its outcome is activation of coagulation with concomitant down regulation of anticoagulant systems and fibrinolysis. Protein C is a single chain vitamin K-dependent plasma serine protease zymogen that upon activation by the thrombin-thrombomodulin (TM) complex down-regulates the clotting cascade by a feedback loop inhibition mechanism.