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Abstract Pulmonary emphysema is the one of the chronic obstructive pulmonary disease (COPD) which is a common chronic lung disorder, usually related to cigarette smoking, representing a major and increasing cause of morbidity and mortality. It is defined as a condition of the lung characterized by abnormal, permanent enlargement of airspaces distal to the terminal bronchiole accompanied by destruction of the alveolar walls without obvious fibrosis. The aim of this study was directed to evaluate role of multi-detector computed tomography (MDCT) in pulmonary emphysema and its classification. This study was conducted on 20 patients referred from Chest Department of Menoufia University Hospital to Radiology Department. They were presented with cough, expectoration, difficult breathing, and wheezes and referred for MDCT of the chest. They were 13 males (65% ) and 7 females (33%) with male to female ratio of 1.8:1 Their ages ranged between 25 and 78years, we noticed that the most common affected age group is the group ages from 61 to 76 years in males (8 patients) and from 20 to 40 years in females (4 patients). In the present study, all patients were subjected to the complete history taking, thorough clinical examination and MDCT. All patients were examined using sixteen detector CT scanners (Toshiba Alexion). The scan parameters used were 120 kVp and 240 mA per slice; tube rotation 0.75 s and slice thickness 1.25 mm. We found that the most common type of pulmonary emphysema was centrilobular emphysema which was encountered in 11 patients (55% of all patients). 9 patients of the patients with centrilobular emphysema were heavy smokers (81%) and 2 were exsmokers. in four smoker patients (46%). We found that the second common type of pulmonary emphysema was paraseptal emphysema which was encountered in 8 patients (40%of all patients). Paraseptal emphysema was also seen associated with centrilobular emphysema Panlobular emphysema was revealed in 4 patients (20%) of all patients, and presented as uniform dilatation of the secondary pulmonary lobules with attenuation less than -950 HU. |