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العنوان
ROLE OF FDG PET-CT IN COMPARISON WITH ENHANCED CT IN DETECTION OF POST THERAPEUTIC COLORECTAL CANCER RECURRENCE AND METASTASIS/
المؤلف
El Sedek,Mohamed Abo Bakr
هيئة الاعداد
باحث / محمدابوبكرالصديق
مشرف / ليلى حسنى حسين
مشرف / مهاعبدالمجيدالشناوى
مشرف / نيفين عبدالمنعم شلبى
تاريخ النشر
2016
عدد الصفحات
160.p:
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2016
مكان الإجازة
جامعة عين شمس - كلية الطب - Radiodiagnosis
الفهرس
Only 14 pages are availabe for public view

from 160

from 160

Abstract

The goal of this study is to elucidate the role of 18F-FDGPET-CT in comparison with enhanced CT for detection of post therapeutic colo-rectal cancer recurrence and metastasis
Fifty patients with histopathologically proven colorectal primary malignancy were evaluated for suspected local recurrence and metastasis using PET/CT and enhanced CT
No age predilection and both sexes were included, Clinical information, image follow-up ,tumer markers, and pathological reports of the patients were reviewed for gold standard
The final diagnosis of distant metastasis and/or local recurrence in post- therapeutic cancer colon was evident in 70% of our patient population with PET /CT sensitivity of 95.6% ,specificity of 91.4% , (NPV) of 88.9%, (PPV) of 96.7% , and diagnostic efficacy of 94.4% and CT sensitivity of 62.6% ,specificity of 48.6 , (NPV) of 33.3% (PPV) of 76.0% , and diagnostic efficacy of 58%
PET/CT is a better method to evaluate post-therapeutic colorectal cancer patients with suspected tumor recurrence or distant metastasis than enhanced CT with significantly higher specificity and sensitivity.