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Abstract Family Asteraceae(Compositae) is one of the largest families of the flowering plants. It is represented in Egypt by 97 genera including 230 species. Onopordum is a genus including about 40 species. Genus Onopordum is represented in Egypt by only two species Onopordum alexandrinum and Onopordum ambiguum. On reviewing the literature, it was found that several plants of the genus Onopordum showed antimicrobial and antitumor activities. Onopordum alexandrinum is used as expectorant and for healing wounds and as a treatment of skin cancers |