الفهرس 
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Abstract
Preterm labor refers to the onset of uterine contractions having sufficient strength and frequency to produce progressive dilatation and effacement of the cervix at gestational age between 20 to 37 weeks (Edward, 2004). The incidence of PTL varies from country to country and from one geographic region to another within a country. It complicates 5-10% of pregnancies and is a leading cause of neonatal morbidity and mortality worldwide it occurs in about 10 % of all Pregnancies in the developed countries and even more often in developing countries (Yussof, 2002).
The aim of this study is to evaluate the effect of using epilate and prontogest on pregnant women with preterm labor who were between the 24th and 34th weeks of gestation and the effect of the two drugs on Doppler parameters.
The present study is a comparative study that compared the effect of epilate and prontogest as a tocolytic drugs on 60 patients with threatened preterm labour and the effect of the two drugs on fetal and maternal Doppler. Patients were divided into two groups as follows:
group 1: This group included 30 patients who received epilate
group 2: This group included 30 patients who received prontogest.
Comparison between the two tocolytic drugs revealed a highly significant difference between groups in response to treatment, the response to epilate was better than Prontogest. Also significant difference between groups was observed in UMA Doppler post treatment and UTA pretreatment. In epilate group UMA and UTA Doppler decreased significantly after treatment, in Prontogest group UTA Doppler decreased. While UMA Doppler did not change significantly.
Difference between groups in UMA Doppler pretreatment and UTA Doppler post treatment wasn’t significant .Also there is no significant difference between groups in neonatal outcome, demographic data and local examination.
Finally we can conclude that difference in doppler is statistically different but clinically not as it is with in the normal range so more studies with larger number of patients is needed to evaluate however there is a real difference or not.