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العنوان
Design, Synthesis and Biological Investigations Of Some 2-Pyridones and Related Derivatves /
المؤلف
Darwish, Salma Abd El-Aziz Ahmed Hassan.
هيئة الاعداد
باحث / سلمى عبد العزيز احمد حسن درويش
مشرف / منير عوض خليل
مشرف / السيد ابو زيد محمد بدوى
مشرف / هيام محمد عبد الهادى عاشور
مشرف / رشا يوسف البياع
الموضوع
Pharmaceutical Chemistry.
تاريخ النشر
2016.
عدد الصفحات
97 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة
تاريخ الإجازة
1/1/2016
مكان الإجازة
جامعة الاسكندريه - كلية الصيدلة - الكيمياء الصيدلية
الفهرس
Only 14 pages are availabe for public view

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Abstract

Pyridine and 2-pyridone units are found in a variety of interesting biologically active compounds whether natural or synthetic. Data show that compounds possessing these simple heterocyclic moieties have been found to possess versatile biological activities including antiulcer, antidiabetic, anti-inflammatory, cardiotonic, anticoagulant, anticancer, antiviral, antibacterial, antifungal and many other activities.
The present thesis is subdivided into the following chapters:
Chapter I
Introduction
Introduction presented a brief literature review describing the various biological activities of pyridine and 2-pyridone units containing pharmaceutically interesting compounds.
Chapter II
Research Objectives
This chapter indicated the rationale upon which the synthesized compounds were designed and prepared. The compounds were designed based on the presence of pyridine and 2-pyridone units.
Chapter III
Discussion
In this chapter, the theories upon which the design and synthesis of the intermediates and final compounds were presented. References were made to the knowledge available in literature as well as the confirmation of the structures of newly synthesized compounds by different chemical and spectral means.