الفهرس 
Chronic UrticariaOnly 14 pages are availabe for public view
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Abstract
A systemic pro-inflammatory and pro-coagulating state occurs in subjects who have both chronic urticaria and metabolic syndrome. To investigate the prevalence and clinical impact of metabolic syndrome in Egyptian patients with chronic urticaria, a case control study was performed included 160 subjects. Metabolic syndrome was assessed by the WHO criteria. Twenty one patients (26.25%) had metabolic syndrome compared to 11.25% in matched controls group (p=.015). metabolic syndrome was higher in chronic urticaria patients with long disease duration. There was a statistical significant difference as regard body mass index, serum triglyceride, high density lipoprotein, fasting blood glucose level and blood pressure. In this study metabolic syndrome was higher in chronic urticaria patients with negative autologous serum skin tests compared with those without metabolic syndrome. Also metabolic syndrome was higher in chronic urticaria with angioedema in comparison with those without angioedema.
We conclude from this study that, patients with severe and uncontrolled chronic urticaria, especially those with high body mass index should be evaluated for metabolic syndrome in order to reduce cardiovascular risk and improve chronic urticaria outcomes.