الفهرس 
Bronchopulmonary Dysplasia
Pneumonia and Bronchiolitis after Bacterial Colonization of the Airways as NeonatesOnly 14 pages are availabe for public view
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Abstract
Background: The quiet epidemic of extreme prematurity rolls on, year after year. Left in the wake of this chronic public health challenge are infants and children with diminished function and reserves, particularly in the brain and the lung. In the lung, this diminished function is called bronchopulmonary dysplasia (BPD). The Aim: The aim of this study is to assess bacterial airway colonization in relation to development of bronchopulmonary dysplasia and evaluate the incidence of concomitant bronchopulmonary dysplasia and bacterial airway colonization. Subjects and Methods: This study was conducted on fifty high-risk neonates for development of BPD. All the patients undergo: Neonates which are premature or mature at the risk for development of BPD. Very low or extremely low birth weight <1.250 kg and less than 32 weeks gestational age. Results: This study was done to identify risk factors of bronchopulmonary dysplasia. Out of 50 preterm neonates who were admitted during the study period, 26 neonates (52%) developed BPD and another 24 premature newborn that didn’t develop BPD. The gestational age of the studied patients ranged from 27 to 32 weeks. The following results were found highly association between BPD and airway colonization accompanied with PROM and sepsis, no statistically significant difference between positive and negative BPD as regard tracheal aspirate 1st only, no statistically significant difference between positive and negative BPD as regard CRP 1st and 2nd only and Highly statistically significant difference between positive and negative BPD as regard Esion. Conclusion: The principal goal of mechanical support of the neonate with respiratory failure is to provide adequate oxygenation and ventilation without associated lung injury. In the present study the risk to develop BPD was associated with longer hospital stay, longer duration of oxygen therapy and mechanical ventilation, also ventilator settings in SIMV which were associated with development of BPD were FIO2, TI and PIP, PEEP.