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Abstract Febrile convulsion is the most common type of seizures in children, the incidence is 2-5% and about 4% of children in the age group of one to six years have at least one episode of febrile convulsion. Febrile convulsions are twice as common in boys as in girls and occurring in children between 5 months and 6 years of age,accounting for 30% of all seizures in children.This is an age dependant, response of the immature brain to fever in children who do not have an intracranial infection, metabolic disturbance or history of afebrile seizures. Eighty to eighty five percent febrile seizures occur between 6 months and 3 years of age with peak incidence at 18 months.Children with a simple febrile seizures has potential risk for recurrence and 2-7% of children may develop epilepsy by adolescence. Contrary to simple febrile seizures, complex febrile seizures are (prolonged>15 minutes, focal, occur more than once in 24 hours).There are different hypotheses about the relationship between neurotransmitters and trace elements such as zinc and febrile seizures. Zinc is a major element of some enzymes plays an important role in the central nervous system and can affect some inhibitory mechanisms of the central nervous system, it also modifies the affinity of the neurotransmitters and thus prevent the excitatory neuronal discharge. |