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العنوان
Role of Diffusion Weighted MRI in
Diagnosis of Endometrial Carcinoma /
المؤلف
Serag, Dena Mamdouh.
هيئة الاعداد
باحث / دينا ممدوح سراج
مشرف / زينب عبد العزيز علي
مشرف / رحاب محمد حبيب
الموضوع
Endometrium - Cancer. Uterine neoplasms - Therapy.
تاريخ النشر
2016.
عدد الصفحات
145 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
الناشر
تاريخ الإجازة
1/6/2016
مكان الإجازة
جامعة المنوفية - كلية الطب - الأشعة التشخيصية
الفهرس
Only 14 pages are availabe for public view

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Abstract

Endometrial carcinoma is the fourth most common female cancer
and the most common malignancy of the female reproductive tract.
Incidence of the disease is increasing due to longevity and rising
levels of obesity. The vast majority of patients with endometrial
carcinoma, about 80% to 90%, present with post menopausal bleeding.
MRI has long been established as a valuable diagnostic tool in the
preoperative diagnostic staging of endometrial carcinoma.
DWI is a new imaging technique which depicts tissue
characteristics based on diffusion motion of water molecules. Initially the
usefulness of this technique was established in central nervous system,
and now DWI is the most accurate modality for diagnosing acute brain
infarction. The technique is applied to the abdominal organs and is known
to depict malignant tumors with high sensitivity. DWI can also provide
values of apparent diffusion coefficient (ADC) of tissues under
investigation. It is known that the ADC values of malignant neoplasms
are lower than those of normal tissues and benign lesions. In endometrial
carcinoma the highly cellular tissues and relatively little extracellular
space lead to restricted motion of water molecules, causing decreased
ADC values.