الفهرس | Only 14 pages are availabe for public view |
Abstract Green Tea is one of the most ancient and popular therapeutic beverages consumed around the world. It is obtained from the plant Camellia sinensis by minimal oxidation during processing. Green tea is reported to contain thousands of bioactive ingredients which are almost contributed by polyphenols which plays a key role in prevention and treatment of many diseases. The main constituent present in green tea is Epicatechein , Catechein , Caffeine , Catechol and Gallic acid. This component is responsible for all the biological activities such as being, anticancer, antioxidant, antidiabetic, antiobesity and antihypertensive as well as antiplatlet, which use in cardiovascular diseases etc.Such study was carried to distinct between two kinds of tea ( Egyptian and Chinese green tea ) in their chemical composition and their reducing power as well as evaluating the effect of their different extracts ( ethanolic as well as cold , hot and boiling water extracts ) on both liver function biomarkers ( AST , ALT , ALP , GGT , Total bilirubin , total protein and albumin ) and oxidative stress biomarkers ( CAT , SOD and MDA ) in rates treated with H2O2 .Ten groups of wister male rats each containing 8 rats, one group of them was kept without any treatment as negative control and the second was treated with 0.5 % H2O2 in drinking water, while the other groups were treated with 0.5 % H2O2 in drinking water besides one of the different extracts of either Egyptian or Chinese green tea.Egyptian green tea was found to contain ash ( 8.77 g/100 g) , total lipids ( 7.1 g/100 g ), crude protein ( 17.6 g/100 g ) and total carbohydrate ( 7.5 g/100 g ) comparing with ash ( 7.8 g/100 g), total lipids ( 7.05 g/100 g ), crude protein ( 18.5 g/100 g) and total carbohydrate ( 7.44 g/100 g) in Chinese green tea. Total phenolics and flavonoids in Egyptian green tea were found to be as follows in the different extract: ethanolic extract ( 259.1 - 185.9 mg/g ), cold water extract ( 221.2 - 165.2 mg/g ), hot water extract ( 169.9 - 121 mg/g ) and boiling water extract ( 113.7 - 87.6 mg/g ), while the same constituents in Chinese green tea showed the following values in the same order of the tested extracted : ethanolic extract ( 229.1 - 181 mg/g ), cold water extract ( 212.7 - 168.4 mg/g ), hot water extract ( 157.4 - 111.5 mg/g ) and boiling water extract ( 89.4 - 79.7 mg/g ). Both Egyptian and Chinese green tea were found to contain 18 of phenolic compounds, among them Caffeine, epicatechin, catechin, cinnamic acid , reverstrol , Salycilic acid and Ferulic acid were the major active constituents.The data showed that there was an improving in both liver function and oxidative stress biomarkers and that Egyptian green tea extracts were more effective than Chinese green tea comparing with positive control. On the other hand, in all tested groups it has been found that ethanolic extract was the more effective one as antioxidant and as protective agent against liver damage. Conclusion : The data showed that Egyptian green tea extracts were more effective than Chinese green tea as antioxidant and ethanol extract was the more effective one as antioxidant. |