الفهرس 
Review of Literature:Only 14 pages are availabe for public view
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Abstract
Leptin is a fat cell-derived hormone signaling the hypothalamus about food intake, the regulation of weight, and sexual behavior. The inhibitory effect of serotonin on libido, ejaculation, and orgasm is well documented. There is an interaction between leptinergic and serotonergic systems in the central nervous system. This study was conducted to evaluate serum leptin levels of the patients with premature ejaculation. The study group consisted of 41 patients with premature ejaculation according to (ISSM) 2014, and 30 healthy controls. The fasting serum leptin levels were measured. Significantly high serum leptin levels in the patients were found. We found that there is there is no correlation between serum leptin IELT (p value > 0.05) but leptin is significantly different between cases and controls. It would appear that leptin may be associated with premature ejaculation.
Key Words:
Leptin , Premature ejaculation