الفهرس 
Multiple sclerosis.Only 14 pages are availabe for public view
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Abstract
Multiple sclerosis is an autoimmune demyelinating disease of the central nervous system. Its prevalence 203 per 100,000 population in 2014. Multiple sclerosis (MS) is the most common inflammatory disorder of the central nervous system and a leading cause of disability in young adults. MS is twice as common in females. It typically presents in young adults between 20 and 50 years of age, with a peak occurring at 30 years of age, although childhood or older age cases occasionally occur. Cognitive impairment may affect patients at any stage of the disease, CI tends to increase with worsening disability and disease duration and could be associated with the onset of a progressive disease course. Major depression (MD) is the most common neuropsychiatric disorder encountered in MS, its prevalence close to 50%, i.e. three times higher than in the general population, depending on the criteria used and the clinical settings of the studies (community, outpatients or tertiary clinics). There is lack of evidence that there is association between personality disorders and the pathology of multiple sclerosis. Magnetic resonance imaging (MRI) of the brain is useful in the diagnosis and treatment of multiple sclerosis (MS), an inflammatory, demyelinating condition of the central nervous system (CNS) that is generally considered to be autoimmune in nature. White matter tracts are affected, including those of the cerebral hemispheres, infratentorium, and spinal cord. MS lesions, known as plaques, may form in CNS white matter in any location; thus, clinical presentations may be diverse.