الفهرس | Only 14 pages are availabe for public view |
Abstract Prolonged exposure to insecticides causes chronic neurological syndrome, malignant tumors, immunosuppressive action, teratogenic effect, abortion and decreased male fertility in experimental animals. Neurochemical changes were reported after chronic exposure to low concentrations of carbamate. Pesticide exposure at relatively low doses may affect brain cells producing a loss of neuron in particular regions of the brain. Methomyl is a carbamate insecticide with anticholinesterase activity. It is one of the most frequently used pesticides in agriculture. Numerous incidents of acute carbamate poisoning have resulted from inhalation of sprays or contamination of crop or food. Imidacloprid is a neonicotinoid insecticide. Imidacloprid toxicity on mammalian tissues has not been adequately evaluated. Imidacloprid cause inflammation in central nervous system. Animal toxicities of imidacloprid are similar to that of toxicities in the parent compound, nicotine. Such toxicities as fatigue, twitching, cramps and weakness leading to asphyxia are seen. Grape is one of the world’s largest fruit crops. Grape seed extract is free radical scavenger activity and suppression of oxidative DNA damage. |