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العنوان
Dermoscopy versus Histopathology in Diagnosis of Some Non-Melanocytic Skin Tumors /
المؤلف
Edrees, Doaa Mohammed Kamel.
هيئة الاعداد
باحث / دعاء محمد كامل إدريس
مشرف / سامح محمد كمال عطية
مشرف / وائل حسام الدين عبد الرازق
مشرف / حسام محمد عبد الوهاب
الموضوع
Skin - Tumors - Diagnosis. Histology, Pathological.
تاريخ النشر
2015.
عدد الصفحات
152 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأمراض الجلدية
تاريخ الإجازة
1/1/2015
مكان الإجازة
جامعة المنيا - كلية الطب - الأمراض الجلدية والتناسلية أمراض الذكورة
الفهرس
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Abstract

Non melanocytic skin tumors refer to a broad class of tumors, including actinic keratosis, basal cell carcinoma, and squamous cell carcinoma, and as a group these are the most frequent cancers occurring in light skinned humans especially BCC. Although these tumors rarely cause death related to metastases, they commonly destroy underlying tissues and should be removed at the earliest possible stage.
Dermoscopy is a simple, non-expensive and non-invasive technique that improves the diagnostic accuracy of non-melanocytic skin tumors. It is one of the most developing and investigative fields of dermatology.
The study included 86 patients with non- melanocytic tumors and divided into 6 groups (BCC, PG, SK, DF, SCC and miscellaneous group) based on the provisional clinical diagnosis.
All patients in this work were subjected to clinical and dermoscopic examination and skin biopsies were taken from all patients to compare the dermoscopic and the histopathologic results.
Its diagnostic accuracy for BCC was 97% and that for PG and SK was 95% and 90% respectively. Meanwhile the diagnostic accuracy for SCC, DF and angiokeratoma was 100% compared with the histopathologic findings.
For dermoscopic diagnosis of BCC the absence of pigment network with the presence of blue-gray globules, large blue-gray nests, structure less area at the periphery or arborizing telangiectasia are very good diagnostic dermoscopic features of BCC but a skin biopsy sometimes is needed as pigmented BCC can mimic melanoma.
The dermoscopic features of SK are not specific but the dermoscopic feature of cerebriform appearance (sulci and gyri) is suggestive of SK and is important in diagnosis.
For PG, the dermoscope is a good diagnostic tool for differentiating warts from PG. Although the diagnostic accuracy for PG was 90% a skin biopsy of doubtful cases of PG is needed as amelanotic melanoma can mimic PG and moreover we found in our work that aggressive BCC gave a clinical and dermoscopic picture similar to PG.
For SCC and adnexal tumors; dermoscopic features are not specific and skin biopsy is a must for diagnosis.
Since novel dermoscopic patterns and features are always reported for skin lesions, dermoscopy is a continuously improving technique of dermatology. Thus, every dermatologist should acquire more in-depth knowledge relating to the dermoscopic features and patterns of the benign and malignant skin lesions.