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العنوان
Synthesis of Novel α-Aminophosphonate Derivatives /
المؤلف
Mohammed, Abdullah Ahmed.
هيئة الاعداد
باحث / عبد الله احمد محمد
مشرف / ابراهيم الطنطاوى السيد
مناقش / محمد حلمي عريف
مناقش / احمد حسين مصطفى
الموضوع
Chemistry, Organic. Nuclear magnetic resonance spectroscopy. Organometallic compounds.
تاريخ النشر
2016.
عدد الصفحات
98
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Organic Chemistry
الناشر
تاريخ الإجازة
13/3/2016
مكان الإجازة
جامعة المنوفية - كلية العلوم - الكيمياء
الفهرس
Only 14 pages are availabe for public view

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Abstract

Organophosphorus compounds are widely used as biologically active
compounds and they have found a wide range of applications in the areas
of industry, agriculture and medicinal chemistry. Among the numerous
types of organophosphorus compounds, α-aminophosphonates are an
important class of molecules due to their applications in biology. For the
importance of α-aminophosphonate compounds this thesis concerned on
synthesis of novel mono and bis-α-aminophosphonate compounds. The
first chapter contains review on the chemistry and biological applications
of α-aminophosphonates including synthesis, reactions and biological
activity. The second chapter concerned on synthesis and biological
evaluation of novel mono and bis-α-aminophosphonate compounds by
using various aldehydes and bis-ketones as carbonyl compounds, mono
and diaromatic amines and triphenyl phosphite in presence of Lewis acid
catalyst. The third chapter describes the general synthetic procedures for
α-aminophosphonates and their characterization data.