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Abstract studies on some antioxidant enzymes gene susceptability to preeclampsia is believed to have a genetic component. several studies have reported associations between polymorphisms of oxidative stress related genes and preeclampsia.the aim of the presnt study was to study the polymorphisms in anti-oxidant genes glutathione s-transferase P1(GSTP1)and Mn-superoxide dismutase (Mn-SOD)in patients with of preeclampsia. therefore seventy four preeclampsia patients and fifty age-matched healthy pregnant female controls were genotyped for GSTP1 and Mn-SOD.DNA analysis was carried out by restriction enzymes(RFLP)for both genes was performed. |