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Abstract The aim of this work is to evaluate the efficacy and safety of ultraviolet A irradiation cross-linking on completion for laser-assisted in situ keratomileusis (LASIK) in risky patients to avoid post Lasik ectasia. For this purpose, 48 eyes of 30 myopic patients were presented for Lasik. They were risky patients with corneal thickness more than 480 um with or without astigmatism, postoperative residual stromal thickness not less than 300 um. After patients’ preparation, all cases had been performed on Schwind Amaris, markers were made to corneal edge and a suction ring was placed to minimize decentration, then 90 μm LASIK flap was created with mechanical microkeratom. Lasik ablation was then applied. On completion of the LASIK excimer ablation procedure, a DROP of 0.1% riboflavin sodium phosphate solution was placed on the bare stromal bed, and left to be soaked in for 60 seconds. Special care was taken not to allow the riboflavin solution to come into contact with the already folded LASIK flap. After adequate riboflavin absorption, the patient was positioned with the UV light (typically 370 um) at a small distance (1-5cm) from the corneal apex for 15 minutes. The study showed an improvement in the spherical error and the results showed a statistically highly significant difference (P <0.001). The study showed also an improvement in the cylindrical error and the results showed a statistically highly significant difference. |