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العنوان
Relationship between Bronchial Asthma and Obesity in Children /
المؤلف
Hussein, Mahmoud Abuelfadl.
هيئة الاعداد
باحث / محمود أبوالفضل حسين
مشرف / غادة محمد المشد
مناقش / غادة محمد المشد
الموضوع
Pediatrics. Bronchial Asthma. Obesity.
تاريخ النشر
2015.
عدد الصفحات
154 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
10/1/2016
مكان الإجازة
جامعة المنوفية - كلية الطب - طب الاطفال
الفهرس
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Abstract

Both obesity and asthma are significant public health problems and epidemics among children (Centers for Disease Control and Prevention, 2009).
Asthma in obese individuals tends to be more severe, does not respond as well to treatment, and is becoming a major public health issue in many countries (Anne et al., 2010).
Increased numbers of eosinophils in peripheral blood and in airway secretions are a characteristic feature of asthma, patients with more severe asthma differ from patients with mild asthma in having more eosinophils in their peripheral blood and in their airways (Wenzel et al., 1999).
Our aim of work was to study the relationship between level of asthma severity and increased level of body mass index (BMI). Our study was conducted at the outpatient pediatric clinic, Department of Pediatrics, Nag-hammady hospital.
This study included eighty children with bronchial asthma. The patients were diagnosed according to Global strategy for Asthma Management and Prevention Classification (Gina, 2012).
The patients divided into 3 groups according to anthropometric measures:
Group 1: Normal weight; according to BMI percentile for age and sex (between 5th and 85th percentile).
Summary
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Group 2: Overweight; according to BMI percentile for age and sex (BMI ≥85th percentile and <95th percentile).
Group 3: Obese; according to BMI percentile for age and sex, (≥95th percentile).
A good history was taken regarding detailed present history, past history and family history and complete clinical examination, pulmonary function tests (FVC, FEV1, and FEV1/FVC) and Complete blood count are done for all patient.
All patients reevaluated after regular treatment of asthma according to level of asthma severity.
Our study revealed the following:
 Greater association between bronchial asthma and obesity.
 Positive relationship between severity of asthma and increase body mass index.
 Reduced response to asthma therapy with increase body mass index.
 Increase relative value of eosinophils cells in all groups, but markedly increase in obese patients.