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Abstract Adult and new born female albino rats of Sprague drawly strain, with an average weight 140±5g and 80±3g respecvely were used in this study, Fifty four new born and adult female albino rats were fed standard diet for one week as an adaptation period. Rats were divided into two main experiments . Experimental design Fifty four female albino rats (24 new born, group I) and (30 adult, group II) were fed standard diet for one week as an adaptation period. New born rats (group I) 24 New born rats (group I) were randomly divided into four subgroups, 6 rats per subgroup. Subgroup (Ia) Control Group: Rats fed standard diet. Subgroup (Ib), Rat fed on sesame seed instead of calcium (calcium free diet): Rats fed on diet free calcium (250 gm dry sesame seeds/kg standard diet ), which allowance an amount of the daily recommended dietary of calcium. (Nzikou et al,2010) ١٦٨ Summary Subgroup (Ic) Rat fed on sesame seed without hulls instead of calcium: Rats fed on diet free calcium (428 gm dry sesame seeds without hulls/kg standard diet), which allowance a amount of the daily recommended dietary of calcium. (Boulbaroud et al ,2008) Subgroup (Id) Rat fed on sesame hulls instead of calcium: Rats fed on diet free calcium (90 gm dry sesame hulls/kg standard diet), which allowance an amount of the daily recommended dietary of calcium.( Nzikou et al,2010) Each group was fed the experimental diet for 45 days Adult rats (group II) 30 adult rats (group II) were randomly divided into two subgroups. Subgroup (II a) Six rats and Subgroup (II b) 24 rats Subgroup (II a) : (Negat. |