الفهرس 
REVIEW OF LITERATUREOnly 14 pages are availabe for public view
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Abstract
The present study was conducted in order to evaluate and compare levels of IL-6 and IL-10 in the GCF and PISF in order to understand the nature of immune response around different dental implant systems.
Twenty patients having twenty clinically healthy dental implants loaded at least from 1 year were enrolled in this study, three dental implant systems were used in this study.
All patients were free from any systemic diseases and non-smokers. They had a good oral hygiene and free from any pathological condition.
PISF sampling was done from selected implants and GCF sampling was done from the antagonist tooth in the same arch.
Selected teeth and implants were isolated by using cotton rolls, then PISF and GCF sampling was done by placing absorbent paper points size 35 for 1 minute in the mesiobuccal and distobuccal sites for each implant and tooth. Paper points contaminated with blood were discarded.
Paper points were carefully placed in sterile low protein binding tubes filled with sterile phosphate buffered saline, then transported for immunohistochemical analysis.
The results of the study showed that
Regarding IL-6, results for Neobiotic implants showed no significant difference in the PISF and the GCF, while for Biomet 3i implants results showed no statistical difference in the levels of IL-6 in both fluids. Also for Astratech implants, IL-6 levels had no significant difference in PISF and GCF.
On the other hand, IL-10 levels in Neobiotic implant group showed significantly higher levels in PISF than GCF. For Biomet 3i implants levels of IL-10 in PISF showed statistical significance higher than GCF, eventually for Astratech implant group IL-10 levels were significantly higher in PISF.
Our results for the total cases showed that there was no significant difference in IL-6 levels in the PISF and GCF, while regarding IL-10 results showed significant higher levels in the PISF than GCF.