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العنوان
Hepatocyte-derived microRNAs as serum biomarkers ofrejection after liver transplantation /
المؤلف
Abdelaleem, Omayma Owees.
هيئة الاعداد
باحث / /اميمة عويس عبد العليم
مناقش / ألفت جميل شاكر
مشرف / أمل رشاد الشهابي
مناقش / سمر على مرزوق
الموضوع
Hepatocyte growth factor.
تاريخ النشر
2014.
عدد الصفحات
117 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الكيمياء الحيوية (الطبية)
تاريخ الإجازة
24/5/2014
مكان الإجازة
جامعة الفيوم - كلية الطب - الكيمياء الحيوية الطبية والبيولوجيا الجزيئية
الفهرس
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Abstract

HCC is a major health problem in Egypt. Liver
transplantation is a lifesaving and effective treatment of end-stage liver
failure. However transplant recipients can suffer from serious side effects
of long-term immunosuppression and they can lose their allografts
because of rejection. Our aim is to evaluate the value of serum miR-122 ,
miR-194 and miR-148a as biomarkers for diagnosis of rejection after
liver transplantation.
Subject and Methods: Blood samples were taken from 30 patients who
prepared to liver transplantation process. Also 50 blood samples from
controls were taken.
The following were done: history taking, general examination, complete
blood picture, liver function tests, hepatitis markers by ELIZA. Serum
was separated for detection of: miR-122, miR-194 and miR-148a by real