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Abstract Probiotics, as well as their metabolites, have been suggested to play an important role in the formation and establishment of a well-balanced intestinal microbiota in human newborns and adults. Although probiotic strains can be isolated from many sources; for human applications the main criteria is being human origin. Over the past decade it has become clear that probiotic and commensal organisms can interact with mucosal immune cells or epithelial cells lining the mucosa to modulate specific functions of the mucosal immune system. This action is remarkably different depending on both the bacterial species and the strain. Therefore, the research aim of the present study was isolation, identification and characterization of novel LAB candidates as potential probiotics with remarkable immunodulatory properties from the feces of healthy breast-fed infants. In addition to investigate the possibility of processing functional yogurt as carrier for the selected novel LAB probiotic strains. |