الفهرس 
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Abstract
This study aimed to: This study was conducted to investigate the influence of 3 levels of cheese whey as a natural source of peroxidase to overcome the negative effect of poly-phenolic naturally found in feed ingredient of rabbit feed. A total of 33 New Zealand White (NZW) male rabbits at 5 weeks of age were used. At the beginning of the experiment, 3 animals were randomly chosen to slaughter and blood samples were taken directly after slaughtering into 3 test tubes. The remaining animals (30 animals) were divided into 5 similar groups (6 animals in each) according to body weight. The control diet was a commercial diet containing barley grains and wheat bran which naturally contain poly-phenolic compounds while 2nd diet contained 6.5% Un-decorticated cotton seed meal (UD CSM) which naturally contain gossypol, to replace 7% of SBM (20% of crude protein level of the control diet) without any additive. The 3rd, 4th and 5th diets were as diet 2, but supplemented with 1, 2 and 3% cheese whey, respectively.The obtained results can be summarized as follows: 1- Chemical analysis of UCSM used in this study showed that it contained DM 92.00%, OM 92.14%, CP 24.00%, CF 23.00%, EE 6.20%, NFE 38.94% and ash 7.86% on DM basis. 2- The peroxidase activity of cheese whey was 28.5 mg/ml. 3- The chemical composition of tested diets indicate that, they were, practically similar in most nutrients content as well as calculated gross energy (MJ/kg DM). However, the tested diet of groups 2, 3, 4 and 5 containing 0, 1, 2 and 3% whey, respectively, had slightlymore CP (16.30, 16.43, 16.56 and 16.70 vs. 16.85%), CF (14.43, 14.43, 14.43and 14.44 vs. 13.92%) and EE (2.64, 2.65, 2.65and 2.66 vs. 2.43%) contents compared with the diet of the control group. 4- Digestion coefficients and nutritive values of the experimental rations: The digestion coefficients of OM, CP, CF, EE, Ash, NDF, ADF, hemi cellulose, cellulose and lignin were improved (P<0.01) with animal in groups R4(2% whey) and group R5(3 % whey) compared with animal fed control diet, group R2 (0% whey) and group R3 (1% whey). However, the difference regarding NFE were improved (P<0.01) with groups R4(2% whey) and group R5(3 % whey) compared with group R2 (0% whey) and group R3 (1% whey) and no significantly differ between control group. Values of TDN, DE and ME were significantly (P<0.01) higher in groups R4(2% whey) and group R5(3 % whey) compared with animal fed control diet, group R2 (0% whey) and group R3 (1% whey). However, DCP was higher (P<0.01) in control compared with the other groups. 5- Live body weight and body weight gain:During the experimental intervals (24 days in each), livebody weight, body weight gainand daily weight gainof groups fed (2 and 3 %<whey) and control group significantly higher as compared to those groups fed (0 % whey. At the end of the experiment, rabbits fed (1, 2 and 3 % whey) and control group had significantly (P<0.05) higher final body weight as <compared to groups fed (0 % whey). 6- Blood constituents: Rabbits fed diets containing 1% whey (group2) had significantly (P≤0.01) more total leukocytes (WBC) as compared to other groups but groups receiving whey had higher than control. Count of RBC was higher in blood of rabbits at the start of experiment than the other groups, but the differences were not significant.Rabbits fed 1% whey had significant (P<0.01) higher Hb% than those in other groups. Rabbits fed control diets had significantly (P≤0.01) higher hematocrit value compared with other groups Significant differences (P≤0.01) were observed in ALT for group fed diet contained 2% whey and control group compared to other groups. On the contrary, group5(3% whey) had higher (P≤0.01) AST compared with the other groups. 7- Immunity parameters : With regard to immunity parameters, rabbits fed diets containing (2 or 3%) and control group had the best value of IgG compared with the other groups, however IgM all groups had value with the normal range but rabbits fed diets containing (0 or 2%) whey had significantly (P≤0.01) higher value compared with the other groups. 8- Economic efficiency ; The best relative economical efficiency was detected with group 3(1% whey being 125.14 when compared with the control group 100%In conclusion, according of the results of the present study, presence of anti-nutritional factors such as phenolic compounds and gossypol in un-decorticated cotton seed meal may limit use in formulating rations for rabbits as well as having a negative impact on utilization of those feedstuffs. The positive results of this current study may encourage the use of whey as cheap natural source of peroxidase enzyme at as low as 1% to decrease the deleterious effects of some anti-nutrient factors present in un-decorticated cotton seed meal to a safe level and to upgrade its nutritive values.