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العنوان
Design and Synthesis of New 2-Aminothiazole and Oxime Derivatives of Ciprofloxacin with Potent Antiproliferative and Antibacterial Activities /
المؤلف
Abdel-Aal, Mohamed Abdel-Aal Ahmed.
هيئة الاعداد
باحث / محمد عبدالعال أحمد عبدالعال
مشرف / جمال الدين علي أحمد حسن
مشرف / صلاح عبدالمطلب عبدالعزيز
مشرف / منتصر شيخون أحمد شيخون
الموضوع
Pharmaceutical chemistry. chemistry, Pharmaceutical.
تاريخ النشر
2015.
عدد الصفحات
173 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العلوم الصيدلية
تاريخ الإجازة
20/9/2015
مكان الإجازة
جامعة المنيا - كلية الصيدلة - كيمياء صيدلية طبية
الفهرس
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Abstract

The present study is concerning with the design, synthesis and biological evaluation of some ciprofloxacin derivatives with antiproliferative and antibacterial activities. The thesis combines four main sections:
1- Introduction: Introduction gave a general account about quinolone derivatives and their different biological activities, in addition to a comprehensive literature survey on ciprofloxacin and other quinolone derivatives as potential leads with antibacterial and anticancer activities.
2- Scope of investigation: This section outlined the goal of this work including the synthesis, biological evaluation and molecular docking studies of some ciprofloxacin derivatives with potent antiproliferative and antibacterial activities.
3- Results and discussion: This section includes explanation of the results obtained from synthesis and biological evaluation of the target compounds. This section is subdivided into three parts: chemistry, biology and molecular docking.
4- Experimental: This section outlines the detailed explanations of different experiments used. This section is also subdivided into three parts: chemistry, biology and molecular docking.