الفهرس 
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Abstract
Tumour markers are biochemical substances produced by tumours and when present in the blood and other body fluids, they could form the basis of an alternative and non invasive technique for the diagnosis and management of malignant diseases.
Tumour markers include various proteins, hormones and enzymes. Oncofetal antigens comprise one particular group of markers, they are present in the fetal blood as well as in cancer patients. Carcinoembryonic antigen (CEA) is probably the foremost oncofetal antigen known. It is a glycoprotein with a molecular weight of about 200.000 Dalton, related to the glycocalyx of neoplastic cells, secreted into blood and other body fluids and its degradation occur in the liver.
CEA was first thought to be a specific indicator for the presence of colorectal carcinoma, but it was found elevated in many benign conditions such as liver diseases, inflammatory bowel disease, chronic lung diseases and in smokers. It is also elevated in many malignancies other than colorectal carcinoma such as stomach, oesophegus and breast cancer.
Bowel preparation for colonoscopy and barium enema may be thought as one of the innocent causes of rise in CEA.
This study aimed at determining if there is any relation between bowel preparation for colonoscopy and rise in serum carcinoembryonic antigen level.
The study included 70 patients undergoing bowel preparation for colonoscopy different causes, excluding those with cancer colon and inflammatory bowel disease, all patients were subjected to through history taking, with emphasis on the presence of any colonic disorder or colorectal operations, full physical examination and routine laboratory tests including complete blood picture, stool analysis c-reacting protein (CRP), urea, creatinine and liver function tests serum CEA is measured before bowel preparation and after bowel preparation but before colonoscopy or radiology.
The cases were presented with bleeding per rectum. chronic diarrhea, constipation and chronic abdominal pain. Un explained iron deficiency anemia.
The results of the present study can be summarized as follows:
1. The incidince of symptoms in patients were referred for colonoscopy was chronic diahrea (34.3%), bleeding per rectum (30%) chronic abd pain (17%), unexplained iron deficiency (8.6%) and after complete resection (2.9%).
2. Mean level of CEA in patient was 1.98 ± 1.15 before and after was 2.2 ± 1.15.
3. Result of colonoscopy was (38%) normal finding, (30%), non specific colitis, angiodysplesia (20%), external pils (4.3%) diverticulosis (2.9%).