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العنوان
Effect Of Endometrial Injury By Office Hysteroscopy In Non-Transfer Cycle On IUI Outcome/
المؤلف
Abd El-Geleel, Amal Abdelrazek.
هيئة الاعداد
باحث / أمل عبد الرازق عبد الجليل إبراهيم
مناقش / عمرو صلاح الدين الحسينى
مناقش / شريف فكرى هنداوى
مشرف / أحمد محمد بهاء الدين أحمد
الموضوع
Ostetrics. Gynecology.
تاريخ النشر
2015.
عدد الصفحات
114 p.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/5/2015
مكان الإجازة
جامعة عين شمس - كلية الطب - Obstetrics and Gynecology
الفهرس
Only 14 pages are availabe for public view

from 132

from 132

Abstract

Uterine receptivity plays a key role in the establishment of successful pregnancies, and its impairment may limit ART success and contribute to the subfertility in many gynecological diseases as endometriosis
IUI is a procedure by which washed spermatozoa are introduced intothe uterine cavity, thereby bypassing several of the natural barriers in the female genital tract. In combination with, or without, controlled ovarian hyperstimulation, it has proven to be not a cost-effective line of treatment for infertility. Its main indications are mild male factor, cervical factor or cases of unexplained infertility.
Currently, most IUI cycles are carried out under ovarian stimulation with the goal of achieving multiple folliculogenesis to increase the fertilization rate, Inadequate uterine receptivity is responsible for approximately two-thirds of implantation failures, whereas the embryo itself is responsible for only one-third of these failures.
Embryonic implantation is a dynamic process of paracrine interactions between the maternal compartment and the conceptus and involves a receptive endometrium and a developmentally competent blastocyst.
Successful implantation requires a competent embryo, a receptive endometrium and a synchronized dialogue between maternal and embryonic tissues. Successful implantation is dependent on a timely progression of a series of biological events during which the embryo undergoes functional interactions with the uterus prepared by the maternal factors.