الفهرس 
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Abstract
Introduction: A newer concept for remineralization is the use of milk and milk products due to the presence of casein. Casein phosphopeptides amorphous calcium phosphate with flouride (CPP-ACPF) is one such agent that has been proposed to have remineralization properties. Aim of the work: this study determined the impact of PEPSI, a carbonated drink, on enamel and dentin with and without application of casein phosphopeptide amorphous calcium phosphate with fluoride (CPP-ACPF). Methods: Eighty sound posterior permanent teeth that had been freshly extracted for orthodontic reasons were selected. Each tooth was longitudinally sectioned bucoo-lingulally and mesio-distally into four sections perpendicular to the long axis of the root. The specimens were divided into 4 groups; 80 specimens each, each divided into 4 subgroups. Group I: artificial saliva (control group). Group II: specimens were subjected to PEPSI drinks. Group III: CPP-ACPF paste applied to the specimens then subjected to PEPSI drinks. Group IV: All the specimens in this group were exposed to PEPSI drinks twice daily for 3 weeks as described in group II (N= 80). After completion of the 3 weeks, the specimens were divided into four subgroups. The specimens of Subgroup a, were examined to show the effect of excessive use of PEPSI drinks without further treatment (N= 20). The other 60 specimens were examined after 3 weeks then treated with CPP-ACPF paste only twice daily and divided into three subgroups b, c and d; 20 specimens each then re-examined after 1, 2 and 3 weeks of paste application, respectively. Results: The application of CPP-ACPF paste was significantly decrease both the enamel surface roughness and the diameter of dentinal tubules. Increase in calcium and phosphorus levels was statistically significant with CPP-ACPF paste application. Conclusions: CPP-ACPF paste is a promising material for remineralization of eroded enamel and dentin surfaces produced by PEPSI drinks.