الفهرس | Only 14 pages are availabe for public view |
Abstract This study aimed to : Thalassemia is an inherited hemolytic disorder caused by partial or complete deficiency ofα or β globin chain synthesis. Regular transfusions are essential for patients with thalassemia to maintain growth and development during childhood and to sustain good quality of life during adulthood. Transfusion therapy with packed red blood cells (PRBCs) is a common practice in the treatment and prevention of many diseases like sickle cell anemia, thalasemia and aplastic anemia.The majority of these patients receive transfusions of PRBCs at some stage of life and some of them become chronic receivers of blood transfusion The study of erythrocyte phenotypes of blood groups in patients and blood donors provides a comparison of the frequency of the most immunogenic genes in each system, being important to decrease the risk of alloimmunization, in addition to estimating the availability of compatible blood, especially in cases of previous delayed hemolytic transfusion reaction DHTR). |