الفهرس 
Reactivity of 4,6-Dimethyl-1H-pyrazolo[3,4-b]pyridin-3-amineOnly 14 pages are availabe for public view
 |  | from | 164 |  |  |
| | | from | 164 | | |
Abstract
In this investigation, when pyrazolopyridine 1 was heated with malonates
reagents in the presence of catalytic amount of acetic acid gave the corresponding
fluorene derivatives 2-4 in 40-55% yields (Scheme 1). A mixture of 4 and N2H4.H2O in ethanol was heated under reflux to give 5
as a white crystal (75%) which was condensed with p-nitrobenzaldehyde in the
presence of a catalytic amount of acetic acid to give a white powde of 6 as a
(86%) (Scheme 2). Diazotization of pyrazolpyridine 1 by using conc. HCl, H2O, and NaNO2
followed by addition of the appropriate amines gave the products 7-9 in 50-70%
yields (Scheme 3).